Sorry men, scientists say ibuprofen may be bad for your testicles

Sorry men, scientists say ibuprofen may be bad for your testicles

The study, which took place in Denmark and France, included 31 adult men under the age of 35.

"Prescribing providers rarely mention these adverse effects with patients when prescribing these medications", she said, according to CNN, noting that the study was "important" and that the use of ibuprofen could have a far greater negative effect on men who already have low fertility. It didn't take long - just two weeks - for the drug to disrupt the hormonal balance and rate of testosterone production of these men.

Richard Quinton, MD, from Newcastle University in England and the Society for Endocrinology, says: "This is a landmark study that elegantly combines clinical and basic research, at both tissue and cellular levels, to show that ibuprofen, a common over-the-counter painkiller, can reversibly hinder testosterone production by testicular cells". Epidemiological studies have shown that NSAID exposure was associated with reduced testosterone and congenital malformations; another study showed a drop in a testosterone metabolite among men who were taking ibuprofen regularly. The painkiller users could potentially face prolonged low testosterone levels after the body loses its ability to compensate, leading to a host of health conditions including muscle weakness and loss, low fertility, and other issues.

Typically seen in older men and smokers, the condition describes when the testes produce an insufficient amount of testosterone. Each dose was 600mg, equivalent to three over-the-counter pills.

Common brands of ibuprofen include Advil and Motrin.

However, in recent years, ibuprofen in particular has been linked to an increased risk of heart attacks and strokes, meaning we should be more cautious when taking anti-inflammatory drugs.

The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use.
Some took 1,200 milligrams of ibuprofen daily, which is the maximum limit as directed, over a six-week period. The remaining 17 volunteers were given a placebo.

The detrimental effects of daily ibuprofen were almost immediate. The condition has been associated with an increased probability of reproductive, cognitive, and physical problems, as well as general mortality.

According to a new study, published in the journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), men who take ibuprofen for months at a time could also be putting their fertility at risk.

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